All States › South Dakota
Opioid Treatment Programs in South Dakota
1 OTP clinics in this state
Source: CMS Opioid Treatment Program Providers public file (May 2026). For 24/7 substance-use crisis: SAMHSA National Helpline 1-800-662-4357 (free, confidential, English/Spanish).
Call 211 for local helpSIOUX FALLS TREATMENT CENTER, LLC
2519 W 8TH ST, SIOUX FALLS, SD 57104