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Opioid Treatment Programs in South Dakota

1 OTP clinics in this state

Source: CMS Opioid Treatment Program Providers public file (May 2026). For 24/7 substance-use crisis: SAMHSA National Helpline 1-800-662-4357 (free, confidential, English/Spanish).

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SIOUX FALLS TREATMENT CENTER, LLC

2519 W 8TH ST, SIOUX FALLS, SD 57104

(605) 332-3236