Opioid Treatment Programs (OTPs) are SAMHSA-certified and CMS-enrolled clinics that dispense methadone, buprenorphine, and naltrexone under federal regulation. Most programs include daily/weekly dosing, individual and group counseling, urine testing, and case management. Many accept Medicaid; sliding-scale fees are common for the uninsured. For substance-use crisis support, call SAMHSA National Helpline 1-800-662-4357 (24/7, free, confidential).